20 Febraury 2019 |       Share
 
 
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CASE STUDIES
Myelotoxicity
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Skin Toxicity Study
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Hepato-Toxicology
Lipid Metabolism
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Estrogenic Drugs Profile

 A complete profile of estrogenic compounds

 

by exploiting the power of molecular imaging, TOP srl improves the quality and reduces the costs and the experimental time for the generation of a pharmacological profile of compounds active on estrogen receptors.


 In vitro assay

Transactivation assay:
- 11 concentrations of compound
Competition assay:
- 11 concentrations of compound + physiological agonist

Cost: 1.500 euro                   
Time: 7 days

 


 In vivo assay

Spatio-temporal and dose-response analysis of compounds on the estrogen receptor:
- 4 animals/group;
- 3 doses of test item, vehicle, reference standard;
- 5 time points;
- single treatment.

Cost: 4.500 euro              
Timing: 10 days

 


 Special Offer 
a complete in vitro and in vivo compound screening:

1 compound starting from 5.000 euro

2 compounds starting from 8.500 euro 

3 compounds starting from 10.000 euro