04 September 2010 |
 
 
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NEWS

Promega – TOP srl Agreement Enables Live Animal Imaging for Cancer Studies
Madison, WI USA. (March 9th, 2010) Promega an...
TOP srl to release the repTOP™ mitoIRE mouse, for measuring cell proliferation in vivo
Measuring cell proliferation in vivo is now p...
TOP srl has a new website!
A new website has been launched by TOP srl...
Bio Europe, Vienna 2009
TOP srl will participate to the Bio Europe 20...

PUBLICATIONS

Biserni A, Giannessi F, Sciarroni AF, et al. In vivo imaging reveals selective peroxisome proliferator activated receptor modulator activity of the synthetic ligand 3-(1-(4-chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-
dimethylpropanoic acid (MK-886). Mol Pharmacol. 2008;73(5):1434-43.

Ottobrini L, Ciana P, Moresco R, et al. Development of a bicistronic vector for multimodality imaging of estrogen receptor activity in a breast cancer model: preliminary application. Eur J Nucl Med Mol Imaging. 2008;35(2):365-78.

Stell A, Belcredito S, Ramachandran B, et al. Multimodality imaging: novel pharmacological applications of reporter systems. Q J Nucl Med Mol Imaging. 2007;51(2):127-38.

Stell A, Biserni A, Della TS, et al. Cancer modeling: modern imaging applications in the generation of novel animal model systems to study cancer progression and therapy. Int J Biochem Cell Biol. 2007;39(7-8):1288-96.

Penza M, Montani C, Romani A, et al. Genistein accumulates in body depots and is mobilized during fasting, reaching estrogenic levels in serum that counter the hormonal actions of estradiol and organochlorines. Toxicol Sci. 2007;97(2):299-307.

Ciana P, Biserni A, Tatangelo L, et al. A novel peroxisome proliferator-activated receptor responsive element-luciferase reporter mouse reveals gender specificity of peroxisome proliferator-activated receptor activity in liver. Mol Endocrinol. 2007;21(2):388-400.

Ciana P, Scarlatti F, Biserni A, et al. The dynamics of estrogen receptor activity. Maturitas. 2006;54(4):315-20.
Ottobrini L, Ciana P, Biserni A, et al. Molecular imaging: a new way to study molecular processes in vivo. Mol Cell Endocrinol. 2006;246(1-2):69-75.

Ottobrini L, Ciana P, Biserni A, et al. Molecular imaging: a new way to study molecular processes in vivo. Mol Cell Endocrinol. 2006;246(1-2):69-75.

Ciana P, Brena A, Sparaciari P, et al. Estrogenic activities in rodent estrogen-free diets. Endocrinology. 2005;146(12):5144-50.

Mussi P, Ciana P, Raviscioni M, et al. Activation of brain estrogen receptors in mice lactating from mothers exposed to DDT. Brain Res Bull. 2005;65(3):241-7.

Maggi A, Ciana P. Reporter mice and drug discovery and development. Nat Rev Drug Discov. 2005;4(3):249-55.

Villa R, Bonetti E, Penza ML, et al. Target-specific action of organochlorine compounds in reproductive and nonreproductive tissues of estrogen-reporter male mice. Toxicol Appl Pharmacol. 2004;201(2):137-48.

Penza M, Bonetti E, Villa R, et al. Whole body action of xenoestrogens with different chemical structures in estrogen reporter male mice. Toxicology. 2004;205(1-2):65-73.

Maggi A, Ottobrini L, Biserni A, et al. Techniques: reporter mice - a new way to look at drug action. Trends Pharmacol Sci. 2004;25(6):337-42.

Ciana P, Raviscioni M, Mussi P, et al. In vivo imaging of transcriptionally active estrogen receptors. Nat Med. 2003;9(1):82-6.

Di Lorenzo D, Villa R, Biasiotto G, et al. Isomer-specific activity of dichlorodyphenyltrichloroethane with estrogen receptor in adult and suckling estrogen reporter mice. Endocrinology. 2002;143(12):4544-51.

Ciana P, Di Luccio G, Belcredito S, et al. Engineering of a mouse for the in vivo profiling of estrogen receptor activity. Mol Endocrinol. 2001;15(7):1104-13.

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