22 October 2017 |       Share
 
 
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PPRE-Luc mouse model
In a recent publication: “LT175 is a novel ...
A novel insights on our repTOP ERE-Luc mouse model
In a recent publication: “Estrogen receptor...
Join TOP srl at the 12th FELASA and 12th SECAL joint congress entitled: ‘Animal Research: Better Science from Fewer Animals’ (10-13 June 2013 Barcelona)
This year at the FELASA meeting, TOP srl will...
Join TOP srl at the American Association for Cancer Research (AACR) Annual Meeting 2013 (April 6-10 2013 Washington DC)
This year at the AACR meeting, TOP srl will p...

OUR TECHNOLOGY

TOP srl is specialized in the production of REPORTER MICE. These transgenic animals, called repTOP™ mice, are genetically modified and produce an easy-to-detect marker in response to specific biologic processes. The marker is produced in all the organs and tissues of the living organism, where the process is acting, and can be easily measured by in vivo imaging.

This enables monitoring physiology, pathology, drug or nutraceutical actions, toxic effects in the intact living organism.

This surplus of information, compared to in vitro methods, combined with the precision of the results and the easy experimental settings, will dramatically reduce attrition rate in the drug discovery pipeline, and offer rapid and more sensitive toxicological testing, while improving ethical standards of animal research.

Follow the webinar on Charles River web site.