TOP srl integrates imaging techniques into the drug discovery process, with the generation of transgenic animals for measuring drug effects on target.
Reporter mice, producing in vivo a biomarker easily detected with imaging techniques, are going to revolutionize the way biological processes can be studied.
Signals are quantitative and are generated with a fast kinetics, enabling the visualization of molecular events in real time, in all the organs, with high precision.
The use of reporter models increases ethical standards of animal research, because the used techniques are non invasive, and this means a reduction of both the stress caused to the mice and of the number of animals required for gathering the necessary information.
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